ablate, abrade, abrase, abrasion, acerbity, acid, acidity, acidulousness, acridity, acridness, acrimony, afflict, affliction, aggravate, aggravation, agonize, ail, anger, animosity, annoy, annoyance, arouse, arrogance, asperity, astringence, astringency, audacity, autacoid, bad humor, bad temper, badger, balls, bark, bedevil, bile, bilge, biliousness, bite, bitter cup, bitter draft, bitter draught, bitter pill, bitter resentment, bitterness, bitterness of spirit, blain, bleb, blemish, blister, blob, bloody, boss, bother, bow, brashness, brass, brazen boldness, brazenness, break, bubble, bulb, bulge, bulla, bump, bunch, burden, burden of care, burl, burn, burn up, button, cahot, cankerworm of care, care, causticity, causticness, chafe, chalone, check, cheek, chide, chine, chip, choler, chutzpah, claw, clump, conceit, concussion, condyle, confidence, convex, convulse, corrosiveness, crack, crackle, craze, cross, crown of thorns, crucify, crust, curse, cut, digestive secretion, discontent, distress, disturb, dowel, ear, effrontery, embitterment, encumbrance, endocrine, enrage, erase, erode, exacerbate, exacerbation, exasperate, exasperation, excoriate, excruciate, exercise, face, fester, file, flange, flap, flash burn, fracture, fray, frazzle, fret, front, gall and wormwood, gash, gastric juice, get, give pain, gnarl, gnashing of teeth, gnaw, gnaw away, goad, grate, grate on, gravel, graze, grievance, grind, gripe, grit, guts, handle, harass, hard feelings, harrow, harry, harshness, haughtiness, heartburning, hector, heroics, hill, hormone, hubris, hump, hunch, hurt, ill humor, ill nature, ill temper, impertinence, improvidence, imprudence, impudence, incense, incise, incision, indiscretion, inflame, inflict pain, infliction, infuriate, injudiciousness, injure, injury, insolence, intestinal juice, irk, irritant, irritate, irritation, jog, joggle, kill by inches, knob, knot, knur, knurl, lacerate, laceration, lesion, lip, load, loftiness, loop, lordliness, lump, maim, make mincemeat of, martyr, martyrize, maul, mole, mordacity, mortal wound, mountain, moxie, mucus, mutilate, mutilation, nag, needle, nerve, nettle, nevus, nip, nub, nubbin, nubble, nuisance, oppression, overbearance, overboldness, overcarelessness, overconfidence, oversureness, overweeningness, pack of troubles, pain, pancreatic juice, papilloma, peck of troubles, peg, pester, pierce, pinch, plague, poison, pomposity, presumption, prick, pride